Giant condylomata acuminata of Buschke-Lowenstein

Surgical method as effective treatment and Imiquimod as adjuvant therapy in an immunocompetent patient

Authors

  • Helena Lucia Barroso dos Reis
  • João Victor Jacomele Caldas
  • Carolina Azevedo Feltz
  • Danielle de Oliveira Machado
  • Lucas Donateli Rosa
  • Marize de Freitas Santos Neves
  • Neide Aparecida Tosato Boldrini
  • Dennis de Carvalho Ferreira
  • Antônio Chambo Filho

Keywords:

Papillomavirus infections, imiquimod, condylomata acuminata

Abstract

Introduction: Giant condylomata acuminata, also known as Buschke-Lowenstein tumor is a rare form of tumor of the anogenital condylomata acuminata, which is a sexually transmitted infection (STI) caused by the human papillomavirus (HPV). Objective: To report a case of giant condylomata acuminata in an immunocompetent patient. Case report: The patient was referred to the Outpatient Clinic for Sexually Transmitted Infections and AIDS at a public hospital in the city of Vitória, Espírito Santo State, Brazil, reporting the onset of progressive growth verrucous lesions on the external genitalia for four months. The patient underwent surgical ablation, and giant condylomata diagnostic confirmation was obtained through histopathology. She was treated with 5% imiquimod cream in routine applications for eight consecutive weeks to avoid recurrence and was also vaccinated for HPV after the procedure. Conclusion: Surgery excision is the treatment of choice in extensive genital condylomata lesions to exclude malignancy. Imiquimod use as adjuvant therapy for reducing recurrence seems to be adequate.

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Author Biographies

Helena Lucia Barroso dos Reis

Infectious Diseases Post-Graduate Program, Universidade Federal do Espírito Santo – Vitória (ES), Brazil.

João Victor Jacomele Caldas

Gynecology and Obstetrics Residency Program, Universidade Federal do Espírito Santo – Vitória (ES), Brazil.

Carolina Azevedo Feltz

Gynecology and Obstetrics Residency Program, Universidade Federal do Espírito Santo – Vitória (ES), Brazil.

Danielle de Oliveira Machado

Gynecology and Obstetrics Residency Program, Universidade Federal do Espírito Santo – Vitória (ES), Brazil.

Lucas Donateli Rosa

Gynecology and Obstetrics Residency Program, UNIMED Vitória – Vitória (ES), Brazil

Marize de Freitas Santos Neves

Gynecology and Obstetrics Department, Universidade Federal do Espírito Santo – Vitória (ES), Brazil.

Neide Aparecida Tosato Boldrini

Gynecology and Obstetrics Department, Universidade Federal do Espírito Santo – Vitória (ES), Brazil.

Dennis de Carvalho Ferreira

Universidade Veiga de Almeida – Rio de Janeiro (RJ), Brazil

Antônio Chambo Filho

School of Sciences of the Santa Casa de Misericórdia de Vitória (EMESCAM), Santa Casa de Misericórdia de Vitória Hospital – Vitória (ES), Brazil.

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Published

2022-01-12

How to Cite

1.
Reis HLB dos, Caldas JVJ, Feltz CA, Machado D de O, Rosa LD, Neves M de FS, et al. Giant condylomata acuminata of Buschke-Lowenstein: Surgical method as effective treatment and Imiquimod as adjuvant therapy in an immunocompetent patient. DST [Internet]. 2022 Jan. 12 [cited 2024 May 28];31(2):66-8. Available from: https://www.bjstd.org/revista/article/view/852

Issue

Section

Case Report