Resistance to protease inhibitors and HIV-1 genetic variability in V3 region in people living with HIV/AIDS

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DOI:

https://doi.org/10.5327/DST-2177-8264-2024361426

Abstract

El VIH-1 se caracteriza por una amplia diversidad genética en todo el mundo, aunque en algunas zonas endémicas la diversidad genética del VIH-1 en personas bajo terapia antirretroviral (TAR) durante 10 años sigue siendo un desafío desconocido.

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References

Capel E, Martrus G, Parera M, Clotet B, Martínez MA. Evolution of the

human immunodeficiency virus type 1 protease: effects on viral replication

© 2024 Sociedade Brasileira de Doenças Sexualmente Transmissíveis

This is an open access article distributed under the terms of the Creative Commons license.

capacity and protease robustness. J Gen Virol. 2012; 93(Pt 12):2625-34.

https://doi.org/10.1099/vir.0.045492-0

Hwang SS, Boyle TJ, Lyerly HK, Cullen BR. Identification of the

envelope V3 loop as the primary determinant of cell tropism in HIV-1.

Science. 1991;253(5015):71-4. https://doi.org/10.1126/science.1905842

Duani H, Aleixo AW, Tupinambás U. Trends and predictors of HIV-1

acquired drug resistance in Minas Gerais, Brazil: 2002-2012. Braz J Infect

Dis. 2017;21(2):148-54. https://doi.org/10.1016/j.bjid.2016.11.009

Chaves YO, Pereira FR, Pinheiro RS, Batista DRL, Balieiro AAS,

Lacerda MVG, et al. High detection rate of HIV drug resistance

mutations among patients who fail combined antiretroviral therapy in

Manaus, Brazil. Biomed Res Int. 2021;8(2021):5567332. https://doi.

org/10.1155/2021/5567332

Junqueira DM, Almeida SEM. HIV-1 subtype B: traces of a pandemic.

Virology. 2016;495:173-84. https://doi.org/10.1016/j.virol.2016.05.003

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Published

2024-09-27

How to Cite

1.
de Sousa Avelino ME, Aguiar Pereira DL, Santos Barbosa M, Ferreira Eleres HN, Bonfim Freitas F, de Souza Fonseca RR, et al. Resistance to protease inhibitors and HIV-1 genetic variability in V3 region in people living with HIV/AIDS. DST [Internet]. 2024 Sep. 27 [cited 2024 Oct. 11];36. Available from: https://www.bjstd.org/revista/article/view/1426

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Letters to the Editor