Chronic genital herpes
case report and literature review
Keywords:genital herpes, immunosuppression, antiviral agents
Genital ulcers are clinical manifestations of diverse etiologies, which can make diagnosis difficult. This case report is about a 64‑year‑old woman with a history of progressive genital ulcer pain for 4 months, despite prior antiviral use. The ulcerated lesion showed perianal involvement. Histopathology revealed neovascularization, edema and inflammatory infiltrate. Despite the use of intravenous acyclovir for 14 days, the improvement was partial. Chronic herpes simplex reveals wart or ulcer of at least one month, usually in immunosuppressed patients. A resistance to antiviral agents is a complication factor, but the treatment response to common infections is usually slower.